Role of Bacteria in Bowel cancer
After identifying that antibiotics prevented the formation of polyp, the scientists tried to feed the antibiotic-treated mice stool from their untreated counterparts to examine, if only bacteria may reverse the drug consequences. Once ingesting the gut bacterium from the untreated mice, the once germ-free mice developed polyps. The researchers additionally transplanted early embryos of the transgenic mice into females of another, cancer-free mouse strain, Swiss Webster. During birth they are inoculated with the bacterium of their surrogate mothers, the mice which are transplanted didn't develop tumors until they reach twenty five weeks, while the genetically identical controls had tumors by twelve weeks. This showed that little changes within the gut microbiota could have a large influence on tumour growth. When the scientists examined the bowels of the animal, they identified that bacterium had invaded the connections between the epithelial cells and intestinal epithelial t