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Showing posts with the label Medical Microbiology Conference

Single-cell RNA-sequence reveals the diversity of trophoblast subtypes and patterns of variation in the human placenta 

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The first cell fate call throughout human embryo development divides the embryonic cells  into 2 lineages, i.e., the inner cell mass (ICM) and therefore the trophectoderm, that any develop into the embryo correct and therefore the main a part of the placenta, respectively. The placenta may be a transient organ that's essential for anchoring the conceptus, preventing its rejection by the maternal system, and transporting nutrients and waste between the foetus and therefore the mother. The placenta performs these functions via multiple specialised cell varieties that result from coordinated genetic , epigenetic and physiological regulation throughout human placentation. Any dysregulation in placentation could result in poor maternity outcomes, like miscarriage, intrauterine growth restriction and pre-eclampsia, and might have an effect on the womb-to-tomb health of each the mother and therefore the foetus. The villus is that the purposeful unit of the placenta and consists of a...

Human microbial detection and study

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Humans have various samples of microbe  colonize from different prats of the body such as gut, skin, mouth and vagina are aggregated with any number of human tissues or fluids from various tracts of the human body. Most of the microbes that usually colonize in humans are co-exist without causing any harmful effects on the humans this are called as commensal . This microbe includes virus, bacteria and fungi with almost around 1600 samples where present. Among all this the gut microbiome plays a highly personalized role, whereas Bacteroides  form an inter-individual variation. There are non-pathogenic microorganisms can invade humans through the metabolism they produce. It is estimated that there are almost 10 times as many microbial cells in the human body. Skin and vaginal sites showed smaller diversity than the mouth and gut, the bacteria, such as  Actinomyces viscosus  and  A. naeslundii , present in the mouth, can be responsible for secreti...

Microbial effect on food spoilage

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Food Spoilage is the process where food deteriorates  and turns in to a form that are not edible to human. There are Various external forces are responsible for the spoilage of food and organisms that are capable of spoiling food. As this includes signs such as change in the appearance colour and texture of the food. The more it is spoiled the more it changes in unpleasant odour and undesirable taste. In general food starts decomposing  and spoils from the time of harvest due to the attack of microorganism and other enzymes. These include bacteria, yeast, moisture, temperature, old and other chemical reaction. Food waste acts as an important component of municipal solid waste. When bacteria  break down the food, the acid and other waste product involves in the process as this can be responsible for spoilage of food. Though this bacterium may or may not be harmful this act upon the food products and produces unpleasant taste and sometimes a harmful effect on h...

Parkinson’s disease: Symptoms, Effects and Research

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Parkinson's disease that affects the central nervous system  is known as the is a degenerative disorder that causes condition such as movement disorders. This causes as nerve cells or neurons in brain become impaired or die. Although this causes loss of neurons when the brain cells fail to produce a chemical known as dopamine as this are responsible for chemical messenger. This could be identified with the movement in the tremor, stiffness in the limbs or the trunk of the body or with the impaired balance. This are found to be in the case of hereditary and can be traced to specific genetic mutations  as sometimes genetic along with environmental factor that trigger the disease. Researches has found that several genetic mutations that are associated with this disease such as alpha-synuclein  gene, DJ-1, PINK1 and LRRK2 as discovering these genes could help in identifying the new way of treatment of disease. There are various primary and secondary symptoms that helps ...

Tuberculosis infection and vaccination

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Tuberculosis is generally caused by the bacterium called Mycobacterium tuberculosis  which affects the lungs and sometimes affects the other parts of the body. This acts as an infectious disease as about 1% of the world population is affected by this infection every year. They are chronic cough with blood containing sputum, night sweats, weight loss, and fever. When the infection is spread to other organs it may cause a serious impact. Tuberculosis acts as a communicable disease which spread through the air. People with infection  in lungs spread infection through a cough, spit, speak and sneeze. These are mainly found in the people who are infected with HIV AIDS and those who smoke. Deduction and treatment must be done in the early period based on the X-ray and microscopic examination of the body fluids. They can be divided into pulmonary  and extrapulmonary . Pulmonary infection is where the disease spread inside the lungs which causes a cough with blo...